Nobody would think that it is OK to deny someone a job as a result of their sex, race or age, and the same should stand for disabled people, too.
We do deny people jobs because of their age: 14 year olds do not get hired as delivery drivers. We do deny people jobs on the basis of their sex: there are no male wet nurses. As to race: there aren’t that many black models being used to advertise tanning salons.
Disabled means differently abled. We don’t hire the blind to be delivery drivers, the deaf as piano tuners nor the dyslexic as subeditors.
Yes we do, and should, deny people a job on the basis of disability. You know, the inability to do the job in question?